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Cimetidine: (Minor) Cimetidine may cause a reduction in the clearance of acyclovir. When utilizing BLAST, Gapped BLAST, and PSI-Blast programs, the default parameters of the respective programs (eg, of XBLAST and NBLAST) can be used (see, eg, http://wwwncbinlmnihgov).
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It will also be understood that normal, conventionally known precautions will be taken regarding the administration of tetracyclines generally to ensure their efficacy under normal use circumstances.